High levels of drug resistance in bacteria that often cause bloodstream infections in hospitals emerged in the first year of the pandemic, a World Health Organization report based on data from 87 countries in 2020 has found. Concerns about so-called superbugs - pathogens that are resistant to existing drugs - are hardly new. The protracted overuse and/or misuse of existing therapies, particularly antibiotics, has helped microbes to become resistant to many treatments, while the pipeline of replacement therapies in development is limited.